According to the National Center for Education Statistics (NCES), USA has over 24,000 public high schools. Please note that the following list includes online secondary schools as well. Here is a ranking of the top 100 largest high schools in United States.
| Rank | High School | Students | Student to Teacher Ratio |
| 1 | Georgia Cyber Academy | 14319 | 40:1 |
| 2 | Pennsylvania Cyber Charter School | 9654 | 28:1 |
| 3 | Commonwealth Charter Academy | 8974 | 27:1 |
| 4 | Ohio Virtual Academy | 8595 | 40:1 |
| 5 | Chicago International Charter School | 8556 | 50:1 |
| 6 | Acero Schools Chicago | 7842 | 187:1 |
| 7 | Somerset Academy of Las Vegas | 6432 | 28:1 |
| 8 | Texas Connections Academy at Houston | 5947 | 40:1 |
| 9 | River Springs Charter School | 5912 | 27:1 |
| 10 | Agora Cyber Charter School | 5867 | 15:1 |
| 11 | Brooklyn Technical High School | 5664 | 24:1 |
| 12 | Visions in Education | 5297 | 29:1 |
| 13 | Carmel High School | 5000 | 18:1 |
| 14 | Allen High School | 4841 | 20:1 |
| 15 | North Shore Senior High School | 4835 | 17:1 |
| 16 | Paramount High School | 4762 | 25:1 |
| 17 | Florida Virtual High School | 4739 | – |
| 18 | Brentwood High School | 4734 | 19:1 |
| 19 | Cypress Bay High School | 4712 | 22:1 |
| 20 | Granada Hills Charter High School | 4650 | 19:1 |
| 21 | Waukegan High School | 4620 | 16:1 |
| 22 | Skyline High School | 4534 | 16:1 |
| 23 | North Star Academy Charter School of Newark | 4490 | 16:1 |
| 24 | Fort Hamilton High School | 4443 | 20:1 |
| 25 | Lewisville High School | 4434 | 16:1 |
| 26 | The Woodlands High School | 4410 | 19:1 |
| 27 | Francis Lewis High School | 4361 | 20:1 |
| 28 | Primavera – Online | 4359 | 44:1 |
| 29 | United High School | 4340 | 19:1 |
| 30 | West Orange High School | 4338 | 23:1 |
| 31 | John A. Ferguson Senior High School | 4304 | 24:1 |
| 32 | Duncanville High School | 4280 | 18:1 |
| 33 | Lake Braddock Secondary School | 4279 | 16:1 |
| 34 | Klein Oak High School | 4244 | 18:1 |
| 35 | Brockton High School | 4242 | 17:1 |
| 36 | Dobie High School | 4238 | 17:1 |
| 37 | Polytechnic High School | 4220 | 25:1 |
| 38 | Downey High School | 4213 | 25:1 |
| 39 | Elsik High School | 4210 | 17:1 |
| 40 | Central High East Campus | 4201 | 22:1 |
| 41 | Lane Tech College Prep High School | 4194 | 21:1 |
| 42 | Warren Township High School | 4158 | 16:1 |
| 43 | Eleanor Roosevelt High School | 4157 | 25:1 |
| 44 | Oak Ridge High School | 4133 | 18:1 |
| 45 | Epic One-on-One Charter High School | 4078 | 942:1 |
| 46 | Deer Park High School | 4074 | 16:1 |
| 47 | Wando High School | 4069 | 16:1 |
| 48 | New Trier Township High School | 4057 | 17:1 |
| 49 | Klein High School | 4046 | 17:1 |
| 50 | Indiana Connections Academy | 4032 | 39:1 |
| 51 | Adlai E. Stevenson High School | 4028 | 14:1 |
| 52 | Interior Distance Education of Alaska (Idea) | 4013 | 125:1 |
| 53 | Midwood High School at Brooklyn College | 4011 | 23:1 |
| 54 | South Carolina Connections Academy | 4009 | 34:1 |
| 55 | Oregon Connections Academy | 4000 | 28:1 |
| 56 | Hastings High School | 3999 | 14:1 |
| 57 | Georgia Connections Academy | 3987 | 38:1 |
| 58 | Lyons Township High School | 3981 | 16:1 |
| 59 | Youth Connection Charter School | 3959 | 26:1 |
| 60 | Robinson Secondary School | 3938 | 16:1 |
| 61 | Odessa High School | 3902 | 17:1 |
| 62 | Hamilton High School | 3900 | 21:1 |
| 63 | Forest Hills High School | 3891 | 20:1 |
| 64 | Tottenville High School | 3856 | 19:1 |
| 65 | East High School | 3854 | 18:1 |
| 66 | Broken Arrow High School | 3853 | 19:1 |
| 67 | Conroe High School | 3805 | 16:1 |
| 68 | Norcross High School | 3805 | 18:1 |
| 69 | T.C. Williams High School | 3783 | 12:1 |
| 70 | Edward R. Murrow High School | 3776 | 19:1 |
| 71 | North Central High School | 3772 | 21:1 |
| 72 | GOAL Academy High School | 3764 | 35:1 |
| 73 | Mill Creek High School | 3759 | 19:1 |
| 74 | James Logan High School | 3750 | 24:1 |
| 75 | Benjamin N. Cardozo High School | 3740 | 23:1 |
| 76 | Wilson High School | 3739 | 26:1 |
| 77 | Warren Central High School | 3736 | 27:1 |
| 78 | Sam Houston High School | 3728 | 15:1 |
| 79 | West Aurora High School | 3724 | 17:1 |
| 80 | South Carolina Virtual Charter School | 3718 | 33:1 |
| 81 | Cypress Ranch High School | 3715 | 18:1 |
| 82 | Lockport Township High School – East Campus | 3711 | 19:1 |
| 83 | Southwest High School | 3708 | 18:1 |
| 84 | Klein Forest High School | 3706 | 14:1 |
| 85 | Klein Collins High School | 3705 | 18:1 |
| 86 | Neuqua Valley High School | 3698 | 17:1 |
| 87 | Permian High School | 3695 | 18:1 |
| 88 | TEAM Academy Charter School | 3694 | 14:1 |
| 89 | Dr. Phillips High School | 3689 | 21:1 |
| 90 | Warren High School | 3678 | 25:1 |
| 91 | Cypress Lakes High School | 3669 | 17:1 |
| 92 | El Camino Real Charter High School | 3660 | 29:1 |
| 93 | Cypress Falls High School | 3653 | 16:1 |
| 94 | Freedom High School | 3638 | 23:1 |
| 95 | John I. Leonard High School | 3635 | 20:1 |
| 96 | Cy-Fair High School | 3630 | 17:1 |
| 97 | Upper Darby Senior High School | 3621 | 15:1 |
| 98 | Santiago High School | 3613 | 25:1 |
| 99 | Fountain Valley High School | 3612 | 28:1 |
| 100 | Jersey Village High School | 3610 | 17:1 |
Broken Arrow High school has 3,961 students as of 2022
imagine being that 1 teacher teaching 14319 students